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Article

Characterization of Stimulated γδ T Cells: Phenotypic Analysis and Implications for Allogeneic Cellular Immunotherapy.

Cells - 2 Dec 2025

Bold Anna, Gross Heike, Bardenbacher Marco, Holzmann Elisabeth, Knop Stefan, Wilhelm Martin

Abstract excerpt

Due to their anti-tumor activity and non-major histocompatibility complex (MHC) binding T cell receptor, γδ T cells are suitable candidates for allogeneic cellular immunotherapy in cancer. Recently, we developed a new protocol called Ko-Op for stimulation of γδ T cells (specifically Vy9Vδ2 T cells) that generates a cell product consisting mainly of γδ T cells with preserved anti-tumor activity targeted for...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 41369406
DOI: 10.3390/cells14231917
PMCID: PMC12691411

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