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Perovskite nanocrystal probes for intraoperative in vitro pathological detection of IDH1 mutation status in glioma.

Journal of neuro-oncology - 8 Dec 2025

Yang Chenxuan, Wang Heda, Liu Minghang, Cai Yuang, Chi Jimei, Huang Liang, Su Meng, Wu Dongdong, Xu Bainan

Abstract excerpt

OBJECTIVE: This study aimed to construct a perovskite quantum dot probe targeting isocitrate dehydrogenase 1 (IDH1) mutation. The probe is intended to enable rapid in vitro pathological diagnosis of IDH1-mutant glioma, guide surgeons in formulating scientific and rational resection strategies during surgery, and facilitate precise individualized intraoperative treatment for glioma patients. METHODS: Via surface...

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Brain Neoplasms
Fluorescent Dyes
Glioma
Isocitrate Dehydrogenase
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 41359079
DOI: 10.1007/s11060-025-05359-5

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IDH1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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