Oral contraceptive use and BRCA penetrance: a case-only study.

doi:10.1158/1055-9965.EPI-09-0024

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Article

Oral contraceptive use and BRCA penetrance: a case-only study.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Jul 2009

Pasanisi Patrizia, Hédelin Guy, Berrino Jacopo, Chang-Claude Jenny, Hermann Silke, Steel Michael, Haites Neva, Hart Jacob, Peled Ronit, Gafà Lorenzo, Leggio Laura, Traina Adele, Amodio Rosalba, Primic-Zakelj Maja, Zadnik Vesna, Veidebaum Toomas, Tekkel Mare, Berrino Franco

Abstract excerpt

BACKGROUND: Women with deleterious mutations in BRCA genes are at increased risk of breast cancer. However, the penetrance of the genetic trait may be regulated through environmental factors. This multinational case-only study tested the interaction between oral contraceptive use and genetic susceptibility in the occurrence of breast cancer. METHODS: We recruited 3,123 patients diagnosed with breast cancer before...

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PMID: 19549808
DOI: 10.1158/1055-9965.EPI-09-0024

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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