Article
Typhi Mykrobe: fast and accurate lineage identification and antimicrobial resistance genotyping directly from sequence reads for the typhoid fever agent Salmonella Typhi.
Genome medicine - 24 Oct 2025
Ingle Danielle J, Hawkey Jane, Hunt Martin, Iqbal Zamin, Keane Jacqueline A, Afolayan Ayorinde O, Ahmed Niyaz, Andleeb Saadia, Ashton Philip M, Bogoch Isaac I, Carey Megan E, Chattaway Marie Anne, Crump John A, Diaz Guevara Paula, Howden Benjamin P, Izumiya Hidemasa, Jacob Jobin John, Judd Louise M, Kapil Arti, Keddy Karen H, Kim Justin Y, Levine Myron M, Morita Masatomo, Nair Satheesh, Octavia Sophie, Okeke Iruka N, Osadebamwen Precious E, Rahman Sadia Isfat Ara, Rokney Assaf, Rasko David A, Shamanna Varun, Sikorski Michael J, Smith Anthony M, Sunmonu Gabriel T, Tagg Kaitlin A, Wick Ryan R, Dyson Zoe A, Holt Kathryn E
Abstract excerpt
BACKGROUND: Typhoid fever results from systemic infection with Salmonella enterica serovar Typhi (Typhi) and causes 10 million illnesses annually. Disease control relies on prevention (water, sanitation, and hygiene interventions or vaccination) and effective antimicrobial treatment. Antimicrobial-resistant (AMR) Typhi lineages have emerged and become established in many parts of the world. Knowledge of local...
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