Back to search

Article

Development and validation of a genome-informed multiplex PCR for specific detection of typhoidal <i>Salmonella</i> serovars

2026-06-03

Abstract excerpt

Enteric fever caused by Salmonella enterica serovars Typhi and Paratyphi A, B and C remains a major public health burden in endemic regions. Existing molecular assays frequently demonstrate limited specificity due to cross-reactivity with non-typhoidal Salmonella (NTS). In this study, we developed and validated a genomics-informed multiplex PCR assay capable of simultaneously differentiating all four typhoidal...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
db775964-d68b-59fb-ae46-04a102e20ff2
DOI
10.64898/2026.06.01.729223
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Development and validation of a genome-informed multiplex PCR for specific detection of typhoidal <i>Salmonella</i> serovarsDOI 10.64898/2026.06.01.729223
Multiplex PCR Assay to Detect High Risk Lineages of <i>Salmonella</i> Typhi and Paratyphi ASemantic proximity
Identification of Five NovelSalmonellaTyphi-Specific Genes as Markers for Diagnosis of Typhoid Fever Using Single-Gene Target PCR AssaysSemantic proximity
Genomic surveillance enables suitability assessment of <i>Salmonella</i> gene targets used for culture-independent diagnostic testingSemantic proximity
An extended genotyping framework for Salmonella enterica serovar Typhi, the cause of human typhoid.Semantic proximity
The molecular epidemiology of enteric fever in South and Southeast AsiaSemantic proximity
Typhi Mykrobe: fast and accurate lineage identification and antimicrobial resistance genotyping directly from sequence reads for the typhoid fever agent <i>Salmonella</i> TyphiSemantic proximity
A global resource for genomic predictions of antimicrobial resistance and surveillance of <i>Salmonella</i> Typhi at PathogenwatchSemantic proximity
Rapid and Specific Differentiation of Salmonella enterica serotypes Typhi and Paratyphi by Multicolor Melting Curve AnalysisSemantic proximity
Uncovering the growing burden of enteric fever: A molecular analysis of Salmonella Typhi antimicrobial resistance.Semantic proximity
Genomic Analysis of <i>Salmonella</i> Typhi from a Typhoid Conjugate Vaccine TrialSemantic proximity
Phylogenetic diversity of the enteric pathogen Salmonella enterica subsp. enterica inferred from genome-wide reference-free SNP characters.Semantic proximity
A real-time PCR for the differentiation of typhoidal and non-typhoidal <i>Salmonella</i>Semantic proximity
Select a neighboring publication to make it the new centre.