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Immunohistochemical Evaluation of T Cell Receptor and T Cell Receptor Beta Constant 1 Expression Distinguishes Benign and Neoplastic Immature T Cell Populations and Reveals Discrete TRBC1/TCR Phenotypes

2025-10-30

Abstract excerpt

<title>Abstract</title> <p>Background: Expression of TRBC1 and TRBC2 is increasingly assessed in the evaluation for clonal T-cell populations. While flow cytometry has repeatedly shown utility in evaluating TRBC 1/2 expression, immunohistochemical (IHC) methods have not been extensively examined, particularly in immature T-cell populations. <h4>Purpose:</h4> This study evaluated TRBC1 IHC staining in formalin-fix...

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Literature Corpus work
67734f09-c1ac-5d84-af29-ae42ff85fe73
DOI
10.21203/rs.3.rs-7658555/v1
Open publication

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Immunohistochemical Evaluation of T Cell Receptor and T Cell Receptor Beta Constant 1 Expression Distinguishes Benign and Neoplastic Immature T Cell Populations and Reveals Discrete TRBC1/TCR PhenotypesDOI 10.21203/rs.3.rs-7658555/v1
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