Article
Creating artificial miR2118a/b to boost yield and broad-spectrum resistance in soybean via CRISPR/Cas9-targeted mutation.
Trends in biotechnology - 1 Apr 2026
Chen Limiao, Ouyang Wenqi, Hu Yanfeng, Peng Lihua, Chen Peike, Guo Wei, Yang Hongli, Xu Juan, Pan Mengyue, Xu Dami, Wang Xinyang, Zhang Chanjuan, Chen Shuilian, Hao Qingnan, Yuan Songli, Huang Yi, Shan Zhihui, Yang Zhonglu, Xia Rui, Hewezi Tarek, Chen Haifeng, Tran Lam-Son Phan, Zhou Xinan, Cao Dong
Abstract excerpt
While regulatory functions of mature miRNAs are well established, the functions of miRNAs* and their potential for genetic engineering in crop improvement remain underexplored. Here, we used clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated protein (Cas9) to generate artificial miR2118a/b (amiR2118a/b) by editing miR2118a/b-5p and obtained several amir2118a/b mutants in soybean...
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