Article
Adaptive evolution and mechanism elucidation for ethanol tolerant Saccharomyces cerevisiae used in starch based biorefinery.
International journal of biological macromolecules - 1 Jan 2025
Xu Zhaoxian, Sha Yuanyuan, Li Muzi, Chen Sitong, Li Jie, Ding Boning, Zhang Yuwei, Li Pingping, Yan Kang, Jin Mingjie
Abstract excerpt
Ethanol tolerant Saccharomyces cerevisiae is compulsory for ethanol production in starch based biorefinery, especially during high-gravity fermentation. In this study, adaptive evolution with increased initial ethanol concentrations as a driving force was harnessed for achieving ethanol tolerant S. cerevisiae. After evolution, an outstanding ethanol tolerant strain was screened, which contributed to significant...
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