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Article

Investigating the causal associations between neuroticism, schizophrenia, and cardiovascular diseases using Mendelian randomization.

European archives of psychiatry and clinical neuroscience - 1 Sept 2026

Pu Liyuan, Zhang Ruijie, Pan Lifang, Li Yiwan, Hu Supei, Huang Yi

Abstract excerpt

BACKGROUND: This study employed two-sample Mendelian randomization (MR) to investigate the potential causal associations between neuroticism, schizophrenia, and various cardiovascular diseases (CVDs), including coronary artery disease (CAD), myocardial infarction (MI), atrial fibrillation (AF), heart failure (HF), stroke, hemorrhagic stroke, and ischemic stroke, along with its subtypes. METHODS: We identified...

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Identifiers

PMID: 41288694
DOI: 10.1007/s00406-025-02163-0

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CAD

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