Article
Comparison of simulated gastrointestinal digestion platforms with varying complexity and sample mass requirements, using common bean (Phaseolus vulgaris L.) as a model.
Journal of the science of food and agriculture - 15 Mar 2026
Bolt Tayah M, Riggs Margaret, Sun Weiyi, Yu Shu, Lerno Larry, Tian Li, Gepts Paul, Palkovic Antonia, Parker Travis A, Bornhorst Gail M, Diepenbrock Christine H
Abstract excerpt
BACKGROUND: Measuring bioaccessible nutrient levels during digestion in a physiologically relevant (dynamic) manner is a bottleneck in plant breeding and food product development. The first aim of this study was to develop and compare four simulated gastric digestion models paired with a static small-intestinal phase for use with small sample masses. The four gastric models tested included three dynamic models,...
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