Article
APOL1 Genotype and Patient Outcomes in US and South African Transplant Recipients With HIV who Received Kidneys From Donors With HIV.
Transplantation - 1 Apr 2026
Freercks Robert, Rodrigues Moreno, Manning Kathryn, Heymann Jurgen, Kopp Jeffrey B, Nagiah Savania, Rana Meenakshi, Florman Sander, Friedman-Moraco Rachel, Stock Peter, Gilbert Alexander, Mehta Shikha, Stosor Valentina, Pereira Marcus R, Morris Michele I, Hand Jonathan, Haidar Ghady, Malinis Maricar, Santos Carlos A Q, Schaenman Joanna, Blumberg Emily A, Wojciechowski David, Odim Jonah, Massie Allan, Selvan Miruthula Tamil, Bagnasco Serena, Segev Dorry, Tobian Aaron A R, Muller Elmi, Durand Christine M, Redd Andrew D
Abstract excerpt
BACKGROUND: Lower allograft survival has been demonstrated in kidney transplant recipients without HIV whose donors have 2 apolipoprotein L1 ( APOL1 ) renal risk variants (RRVs). The effects of APOL1 RRV on kidney transplant outcomes in people with HIV have not been fully assessed. METHODS: Genomic DNA was analyzed for APOL1 RRV genotype using a probe-based assay in HIV-positive kidney transplant recipients (R +...
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