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Article

Empirical Drug Dosage Validates Pharmacogenomic Associations in All of Us.

Clinical and translational science - 1 Nov 2025

Matthias Jan, Falaguera Maria J, Altman Russ B

Abstract excerpt

The All of Us research program, a national longitudinal study conducted by the US National Institutes of Health, provides robust medical history, drug dosage and genomic data from a diverse population. All of Us offers an opportunity to discover novel correlations between drug dosage and genetic variation. However, first it is necessary to evaluate the quality and quantity of the data and its ability to replicate...

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Share to Cytochrome P-450 Enzyme System
Share to Dose-Response Relationship, Drug

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 41241757
DOI: 10.1111/cts.70406
PMCID: PMC12619694

Genes

CYP2C19
CYP2C9
CYP3A5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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