Article
Dosing recommendations for pharmacogenetic interactions related to drug metabolism.
Pharmacogenetics and genomics - 1 Jul 2016
Filipski Kelly K, Pacanowski Michael A, Ramamoorthy Anuradha, Feero William Gregory, Freedman Andrew N
Abstract excerpt
OBJECTIVE: Pharmacogenomic studies have established the important contribution of drug-metabolizing enzyme genotype toward drug toxicity and treatment failure; however, clinical implementation of pharmacogenomics has been slow. The aim of this study was to systematically review the information on drug-metabolizing enzyme pharmacogenomics available in the US drug labeling, practice guidelines, and recommendations....
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