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Investigation of Genetic Polymorphisms in Inducible Nitric Oxide Synthase and Suppressor of Cytokine Signaling Genes and Pain After Root Canal Treatment.

Biochemical genetics - 1 Aug 2026

Nascimento Wayne Martins, da Silva Erlange Andrade Borges, Meyfarth Sandra Regina Santos, da Silva Guimarães Ludmila, Limoeiro Ana Grasiela, Ribeiro Heitor Ganier, Küchler Erika Calvano, Baratto-Filho Flares, Silva-Sousa Alice Corrêa, Sousa-Neto Manoel Damião, Antunes Lívia Azeredo Alves, Antunes Leonardo Santos

Abstract excerpt

Pain following endodontic treatment is a common complication potentially linked with genetic polymorphisms that modulate pain biomarkers. Hence, this study aimed to explore the association between pain experienced after endodontic treatment and genetic polymorphisms in the genes encoding inducible nitric oxide synthase (NOS2), and suppressor of cytokine signaling (SOCS1). The study involved 108 participants with...

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NOS2 gene
SOCS1 gene
Nitric Oxide Synthase Type II
Polymorphism, Single Nucleotide

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Suppressor of Cytokine Signaling 1 Protein

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Identifiers

PMID: 41240168
DOI: 10.1007/s10528-025-11276-z

Genes

NOS2
SOCS1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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