Article
Association between single-nucleotide polymorphisms in serotonin receptor 2A and melatonin receptor 1A genes and pain after root canal treatment.
International endodontic journal - 1 Sept 2023
Meyfarth Sandra Regina Santos, Tavares Jhenyfer da Silva, Guimarães Ludmila da Silva, Silva Erlange Andrade Borges, Gaio Daniella Cristina, Ecker Mainara Bassetto, Brancher João Armando, Küchler Erika Calvano, Silva-Sousa Alice Corrêa, de Sousa-Neto Manoel Damião, Antunes Lívia Azeredo Alves, Antunes Leonardo Santos
Abstract excerpt
AIM: This study aimed to investigate whether single-nucleotide polymorphisms (SNPs) in the genes encoding 5-HTR2A (5-Hydroxytryptamine (serotonin) receptor 2A) and MTNR1A (melatonin receptor 1A) may contribute to postoperative pain perception after root canal treatment. We hypothesised that SNPs in HTR2A and MTNR1A genes were associated with postoperative pain after root canal treatment. METHODOLOGY: This genetic...
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