Inducible Nitric Oxide Synthase Polymorphisms and Nitric Oxide Levels in Individuals with Chronic Periodontitis.

doi:10.3390/ijms18061128

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Article

Inducible Nitric Oxide Synthase Polymorphisms and Nitric Oxide Levels in Individuals with Chronic Periodontitis.

International journal of molecular sciences - 15 Jun 2017

Scarel-Caminaga Raquel M, Cera Flávia F, Pigossi Suzane C, Finoti Livia S, Kim Yeon J, Viana Aline C, Secolin Rodrigo, Montenegro Marcelo F, Tanus-Santos José E, Orrico Silvana R P, Cirelli Joni A

Abstract excerpt

This study aimed to investigate whether the -1026(A>C)(rs2779249) and +2087(A>G)(2297518) polymorphisms in the NOS2 gene were associated with chronic periodontitis (CP) and with salivary levels of nitrite (NO₂-) and/or nitrate + nitrite (NOx). A group of 113 mixed-race patients were subjected to periodontal, genetic, and biochemical evaluations (65 CP/48 periodontally healthy subjects). DNA was extracted from...

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PMID: 28617311
DOI: 10.3390/ijms18061128
PMCID: PMC5485952

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NOS2

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