Article
The rs216009 single-nucleotide polymorphism of the CACNA1C gene is associated with phantom tooth pain.
Molecular pain - 1 Jan 2000
Morii Masako, Ohka Seii, Nishizawa Daisuke, Hasegawa Junko, Nakayama Kyoko, Ebata Yuko, Soeda Moe, Fukuda Ken-Ichi, Yoshida Kaori, Koshika Kyotaro, Ichinohe Tatsuya, Ikeda Kazutaka
Abstract excerpt
Phantom tooth pain (PTP) is a rare and specific neuropathic pain that occurs after pulpectomy and tooth extraction, but its cause is not understood. We hypothesized that there is a genetic contribution to PTP. The present study focused on the CACNA1C gene, which encodes the α1C subunit of the Cav1.2 L-type Ca2+ channel (LTCC) that has been reported to be associated with neuropathic pain in previous studies. We...
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