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Article

B lymphocytes and tertiary lymphoid structures have a prognostic impact on penile squamous cell carcinoma.

The journal of pathology. Clinical research - 1 Nov 2025

Zavillová Nicolette, Waldauf Petr, Kendall Bártů Michaela, Čapka David, Hojný Jan, Prouzová Zuzana, Matěj Radoslav, Zachoval Roman, Hrudka Jan

Abstract excerpt

Several prognostic markers, including tumor-infiltrating lymphocytes, which have been recently identified in penile squamous cell carcinoma (pSCC), have focused mostly on T cells. The prognostic role of B cells and tertiary lymphoid structures (TLSs) has not yet been sufficiently described. We examined whole tissue sections histopathologically for TLSs and immunohistochemically for CD20 and CD138. The B-cell...

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Topics

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Share to Antigens, CD20
Share to B-Lymphocytes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Biomarkers, Tumor

Share to Carcinoma, Squamous Cell

Share to Immunohistochemistry

Share to Lymphocytes, Tumor-Infiltrating

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Share to Tumor Suppressor Protein p53

Source

Open in PubMed Open full text

Identifiers

PMID: 41235705
DOI: 10.1002/2056-4538.70059
PMCID: PMC12616500

Genes

EGFR
KMT2D

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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