Exploring the mediating role of potential therapeutic genes in the pathogenesis of hypopituitarism through the metabolites from a genomic perspective.

Abstract excerpt

Hypopituitarism is a severe endocrine disorder characterized by a partial or complete hormone deficiency in the anterior or posterior pituitary gland. Current treatment relies on hormone replacement therapy, which is unable to mimic normal physiological circadian rhythm precisely, and long-term hormone replacement therapy can result in a variety of adverse effects. This study aimed to identify potential drug...

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