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Article

Integrative multi-omics analysis identifies endocrine-disrupting chemical-related molecular mechanisms in migraine.

The journal of headache and pain - 8 Jun 2026

Ren Yinfan, Xu Ziqi, Xu Zifei, Zhang Guifang, Huang Huanjie, Wang Chuhuai, Hu Xiao-Qian

Abstract excerpt

BACKGROUND: Migraine is a highly prevalent, heritable neurological disorder with a marked female predominance, indicating substantial hormonal contributions to disease pathophysiology. Endocrine-disrupting chemicals (EDCs) are ubiquitous environmental contaminants that interfere with hormonal signaling and have been linked to multiple diseases, yet their molecular contribution to migraine remains unclear. This...

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Source

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Identifiers

PMID: 42260332
DOI: 10.1186/s10194-026-02412-0
PMCID: PMC13471568

Genes

B9D2
PNKP
HTRA1
OSBPL10
PRDM16

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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