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[Association between lipid levels and the risk of Graves' ophthalmopathy: Mendelian randomization and clinical observational analysis].

[Zhonghua yan ke za zhi] Chinese journal of ophthalmology - 11 Nov 2025

Zhu M, Guo M J, Cao J M, Xie B Y, Zhang F, Xiong W

Abstract excerpt

Objective: To investigate the association between lipid levels and the risk of Graves' ophthalmopathy (GO). Methods: This study employed Mendelian randomization (MR) with a retrospective cross-sectional analysis. Summary data for lipids and GO were obtained from the genome-wide association studies (GWAS) released between 2013 and 2023, and two-sample MR was used to explore the causal relationship between lipids...

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Identifiers

PMID: 41218900
DOI: 10.3760/cma.j.cn112142-20241216-00581

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