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Article

Causal linkage of Graves' disease with aging: Mendelian randomization analysis of telomere length and age-related phenotypes.

BMC geriatrics - 31 Oct 2024

Hu Jingwen, Zhang Jin, Liu Yingshu, Qin Jiahui, Bai Haixia, Qin Xiaosong

Abstract excerpt

BACKGROUND: Aging is an irreversible progressive decline in physical function. Graves' disease (GD) is a common cause of hyperthyroidism and is characterized by elevated levels of the thyroid hormone (TH). High TH levels are associated with aging and a shortened lifespan. The causal relationship between GD and aging has yet to be investigated. METHODS: We used genome-wide association study (GWAS) datasets and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39482583
DOI: 10.1186/s12877-024-05379-2
PMCID: PMC11526548

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