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Article

CD36 is required for human sapovirus propagation.

Journal of virology - 25 Nov 2025

Oka Tomoichiro, Okemoto-Nakamura Yuko, Takagi Hirotaka

Abstract excerpt

Human sapoviruses (HuSaVs), which cause acute gastroenteritis, are highly diverse. Fifteen HuSaV genotype strains (GI.1-7, GII.1-5, -8, and GV.1-2) were efficiently propagated in the human duodenum-derived cell line HuTu80 when supplemented with conjugated bile acid (T. Oka, T.-C. Li, K. Yonemitsu, Y. Ami, et al., J Virol 98:e00639-24, 2024, https://doi.org/10.1128/jvi.00639-24). However, the host cellular...

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Caliciviridae Infections
CD36 Antigens
Cell Line
Cricetulus
Gene Knockout Techniques
Genotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Virus Replication

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Identifiers

PMID: 41190813
DOI: 10.1128/jvi.01325-25
PMCID: PMC12646008

Genes

CD36

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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