Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic risk factors in rheumatoid arthritis: A Mendelian randomization study of chronic kidney disease in European populations.

Medicine - 17 Oct 2025

Yang Xinyan, Yang Huiting, Yi Fangyu, Yan Yici, Jin De, Chen Hongyu, Zeng Jiali

Abstract excerpt

Rheumatoid arthritis (RA) is a heritable autoimmune disease linked to chronic kidney disease (CKD) in observational studies. However, whether this association is causal and driven by shared genetic risk remains unclear, warranting genetic investigation. To investigate possible causal relationships between RA and different CKD subtypes, we used Mendelian randomization (MR) analyses with data from genome-wide...

Read the complete abstract on PubMed

Topics

Humans
Arthritis, Rheumatoid
Europe
Genetic Predisposition to Disease
Genome-Wide Association Study
Glomerulonephritis, IGA

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Mendelian Randomization Analysis

Polymorphism, Single Nucleotide

Renal Insufficiency, Chronic

Risk Factors

White People

Source

Open in PubMed Open full text

Identifiers

PMID: 41189266
DOI: 10.1097/MD.0000000000044957
PMCID: PMC12537118

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 24 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic risk factors in rheumatoid arthritis: A Mendelian randomization study of chronic kidney disease in European populations.PMID 41189266Read ↗

The causal effect of juvenile idiopathic arthritis on IgA nephropathy: A Mendelian randomization study.Semantic proximity Read ↗

Rheumatoid Arthritis, Circulating Inflammatory Proteins, and Hypertension: A Mendelian Randomization Study.Semantic proximity Read ↗

Genetic predisposition to smoking is associated with risk of rheumatoid arthritis: a Mendelian randomization study.Semantic proximity Read ↗

Rheumatoid arthritis and the risk of major cardiometabolic diseases: a Mendelian randomization study.Semantic proximity Read ↗

Two-sample Mendelian randomization analysis unveils a potential genetic association between rheumatic diseases and the risk of idiopathic pulmonary fibrosis.Semantic proximity Read ↗

Genetic causality between modifiable risk factors and the risk of rheumatoid arthritis: Evidence from Mendelian randomization.Semantic proximity Read ↗

Mendelian Randomization Analysis of the Causal Link Between Rheumatoid Arthritis and Interstitial Lung Disease.Semantic proximity Read ↗

A practical guide for nephrologist peer reviewers: understanding and appraising Mendelian randomization studiesSemantic proximity Read ↗

Genetic link between rheumatoid arthritis and autoimmune liver diseases: A two-sample Mendelian randomization study.Semantic proximity Read ↗

Rheumatoid arthritis increases the risk of heart failure: results from the cross-sectional study in the US population and mendelian randomization analysis in the European populationSemantic proximity Read ↗

Effect of Higher Glycated Hemoglobin (HbA1c) Levels on rheumatoid arthritis Risk:A Mendelian Randomization StudySemantic proximity Read ↗

Does inflammatory bowel disease promote kidney diseases: a mendelian randomization study with populations of European ancestrySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.