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Article

Causal association between gastrointestinal diseases and coronary artery disease: a bidirectional Mendelian randomization study.

Frontiers in endocrinology - 1 Jan 2024

Wang Zhuoxi, Ban Jifang, Zhou Yabin, Qie Rui

Abstract excerpt

Background: Coronary artery disease (CAD) has been a dominating reason of mortality globally due to its complexity of etiology. A variety of gastrointestinal disorders (GDs) have been accounted to be related to CAD. Thus, this study aims to determine their causal relationship by two-sample Mendelian randomization (MR) analysis. Methods: Single-nucleotide polymorphisms (SNPs) relevant to 22 GDs were employed as...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39473508
DOI: 10.3389/fendo.2024.1458196
PMCID: PMC11518705

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