Article
Predicting phenotypic traits of prokaryotes from protein domain frequencies.
BMC bioinformatics - 24 Sept 2010
Lingner Thomas, Mühlhausen Stefanie, Gabaldón Toni, Notredame Cedric, Meinicke Peter
Abstract excerpt
BACKGROUND: Establishing the relationship between an organism's genome sequence and its phenotype is a fundamental challenge that remains largely unsolved. Accurately predicting microbial phenotypes solely based on genomic features will allow us to infer relevant phenotypic characteristics when the availability of a genome sequence precedes experimental characterization, a scenario that is favored by the advent...
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