Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Clinical characteristics and molecular heterogeneity in Follicular lymphoma with extranodal involvement.

Genome medicine - 24 Oct 2025

Li Rui-Chi, Tang Wei, Zhang Hui-Lai, Wang Xian-Huo, Sun Rui, Wang Nan, Xu Tian-Yuan, Chen Si-Yuan, Feng Yan, Shen Rong, Wang Li, Cheng Shu, Xu Peng-Peng, Yi Hong-Mei, Dong Lei, Zheng Zhong, Zhao Wei-Li

Abstract excerpt

BACKGROUND: Follicular lymphoma (FL) represents the most common subtype of indolent non-Hodgkin's lymphoma. Extranodal involvement (ENI) indicates a poor clinical outcome in patients who received rituximab-based immunochemotherapy. Recent studies indicate that genetic alterations and tumor microenvironment dysregulation drive extranodal dissemination and lymphoma progression. However, the molecular mechanisms...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Aged, 80 and over

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Biomarkers, Tumor

Share to Lymphoma, Follicular

Share to Mutation

Share to Prognosis

Share to Rituximab

Share to Tumor Microenvironment

Source

Open in PubMed Open full text

Identifiers

PMID: 41137062
DOI: 10.1186/s13073-025-01557-y
PMCID: PMC12553287

Genes

CARD11
CREBBP
KMT2D
STAT6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Clinical characteristics and molecular heterogeneity in Follicular lymphoma with extranodal involvement.PMID 41137062Read ↗

Advances in the multi-omics landscape of follicular lymphomaSemantic proximity Read ↗

The follicular lymphoma epigenome regulates its microenvironment.Semantic proximity Read ↗

Biology as vulnerability in follicular lymphoma: genetics, epigenetics, and immunogeneticsSemantic proximity Read ↗

Integrative genomic and transcriptomic analysis reveals genetic alterations associated with the early progression of follicular lymphoma.Semantic proximity Read ↗

Genomic landscape of follicular lymphoma across a wide spectrum of clinical behaviors.Semantic proximity Read ↗

Novel insights into the pathogenesis of follicular lymphoma by molecular profiling of localized and systemic disease forms.Semantic proximity Read ↗

Duodenal-type and nodal follicular lymphomas differ by their immune microenvironment rather than their mutation profiles.Semantic proximity Read ↗

Novel insights into the pathogenesis of follicular lymphoma by molecular profiling of localized and systemic disease formsSemantic proximity Read ↗

Navigating the Heterogeneity of Follicular Lymphoma and its Many Variants: An Updated Approach to Diagnosis and Classification.Semantic proximity Read ↗

Vulnerabilities in the tumor and microenvironment in follicular lymphoma.Semantic proximity Read ↗

Epidemiology of Follicular Lymphoma.Semantic proximity Read ↗

Genetic and Transcriptomic Profiles Identify Potential Therapeutic Targets of Concurrent Follicular and Diffuse Large B-Cell Lymphoma and Transformed Follicular Lymphoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.