Article
Duodenal-type and nodal follicular lymphomas differ by their immune microenvironment rather than their mutation profiles.
Blood - 18 Oct 2018
Hellmuth Johannes C, Louissaint Abner, Szczepanowski Monika, Haebe Sarah, Pastore Alessandro, Alig Stefan, Staiger Annette M, Hartmann Sylvia, Kridel Robert, Ducar Matthew D, Koch Peter, Dreyling Martin, Hansmann Martin-Leo, Ott German, Rosenwald Andreas, Gascoyne Randy D, Weinstock David M, Hiddemann Wolfgang, Klapper Wolfram, Weigert Oliver
Abstract excerpt
Duodenal-type follicular lymphoma (DTFL) is a rare and highly indolent follicular lymphoma (FL) variant. It is morphologically and immunophenotypically indistinguishable from typical FL, characterized by restricted involvement of intestinal mucosa, and lacks extraintestinal manifestations. The molecular determinants of this distinct clinical behavior are largely unknown. Thirty-eight diagnostic biopsies from...
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