Exploring the genetic landscape of COVID-19 susceptibility and severity among patients in Türkiye.

doi:10.1186/s12920-025-02200-w

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Article

Exploring the genetic landscape of COVID-19 susceptibility and severity among patients in Türkiye.

BMC medical genomics - 30 Dec 2025

Er Ahmet Gorkem, Çakır Yavuzhan, Er Berrin, Burduroğlu Hüseyin Cahit, Çakmak Mehmet, Özışık Lale, Tanrıöver Mine Durusu, Topeli Arzu, Son Yeşim Aydın, Ünal Serhat

Abstract excerpt

BACKGROUND: One of the most challenging factors for clinicians in managing COVID-19 has been differences in the clinical course. To investigate the parameters associated with severe disease in detail, along with examining known risk factors such as advanced age and comorbidities, understanding pe...

Topics

Humans
COVID-19
Genetic Predisposition to Disease
Female
Male
Middle Aged
SARS-CoV-2
Severity of Illness Index
Aged
Polymorphism, Single Nucleotide
Gene Frequency
Angiotensin-Converting Enzyme 2
Adult

Source

Open in PubMed Open full text

Identifiers

PMID: 41466405
DOI: 10.1186/s12920-025-02200-w
PMCID: PMC12888178

Genes

ACE2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-41466405-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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