Highly Recurrent Multinucleotide Mutations in SARS-CoV-2.

Abstract excerpt

Multinucleotide mutations simultaneously replace multiple nucleotides. They are a significant contributor to evolution and disease, as well as to misdiagnosis, misannotation and other biases in genome data analysis. Multinucleotide mutations are generally thought to be rare and random events. However, by processing over 2 million publicly shared genomes, we show that certain multinucleotide mutations are highly...

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