Genetic regulation of the estrogen receptor and inherited predisposition to breast cancer.

Abstract excerpt

For many families severely affected with breast cancer, no inherited causal allele has been detected in any tumor suppressor gene. In an effort to understand the genetics underlying breast cancer in these families, we evaluated 136 such families for coinheritance of breast cancer with each of 79 common variants reported as high-confidence "risk alleles" for breast cancer by meta-analyses of genome-wide...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Breast Neoplasms
• Share to Estrogen Receptor alpha