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Article

The interplay between polygenic susceptibility and discrimination on depressive symptoms: a prospective cohort study.

Aging & mental health - 1 Mar 2026

Khatun Toslima, Norton Sam, Hackett Ruth A

Abstract excerpt

OBJECTIVES: This study investigated the interplay between perceived discrimination and polygenic propensity on depressive symptoms cross-sectionally and longitudinally. METHOD: Data were from the English Longitudinal Study of Ageing (N = 4950). Perceived discrimination (2010-11) and depressive symptoms (CES-D, 2010-17) were assessed. Depressive symptoms polygenic scores (PGS) were calculated using summary...

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PMID: 41126579
DOI: 10.1080/13607863.2025.2569654

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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