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Article

Genetic regulation of exosome biogenesis pathway in human adipose and muscle tissue and association with obesity and insulin resistance.

International journal of obesity (2005) - 1 Feb 2026

Das Swapan K, Deep Gagan, Comeau Mary E, Langefeld Carl D

Abstract excerpt

BACKGROUND: Animal studies provide evidence of a link between exosome profile, obesity and insulin resistance (IR). Although it is known that exosomes mediate cell-cell communication via their macromolecular cargo, the genetic factors regulating exosomes in humans are largely unknown. METHODS: Leveraging genome-wide expression and genotype data from the African American Genetics of expression and Metabolism...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41109913
DOI: 10.1038/s41366-025-01933-z
PMCID: PMC13293148

Genes

AHNAK
RAP2A

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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