Article
Potential sex-specific associations between MTHFR C677T polymorphism and thyroid autoantibodies in spontaneous abortion: A retrospective study in the Lingnan region of China.
Journal of reproductive immunology - 1 Dec 2025
Li Ying, Diao Ruiying, Ou Yanghong, Li Dongdong, Yu Shuaishuai, Ye Xiaofeng, Guo Yan, Xu Xianfeng, Tan Qiao, Wang Liping
Abstract excerpt
The methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism and thyroid autoimmunity are established risk factors for spontaneous abortion (SA). We aimed to explore the relationship between these factors in both sexes within the SA cohort from the Lingnan region of China. This retrospective cross-sectional study enrolled 474 women and 235 men at Shenzhen Second People's Hospital from July 2019 to November...
Read the complete abstract on PubMedTopics
- Humans
- Female
- Male
- Methylenetetrahydrofolate Reductase (NADPH2)
- Autoantibodies