Article
Investigating the Association of MTHFR C677T Gene Polymorphism with Recurrent Spontaneous Abortion Among Azerbaijani Women from Northwest Iran.
Genetic testing and molecular biomarkers - 1 Oct 2023
Moqadami Amin, Rezaei Abedeh, Ahmadi Alireza, Badamchizadeh Parastoo, Karimi Zahra, Molaei Faezeh, Khalaj-Kondori Mohammad
Abstract excerpt
Background: Recurrent spontaneous abortion (RSA), defined as two or more succeeding abortions during 20 weeks of gestation, affects 3-5% of pregnancies. Several studies have found that most women with RSA had at least one (and sometimes two copies) of the methylenetetrahydrofolate reductase (MTHFR) C677T variant. Materials and Methods: The study involved 118 women who had two or more spontaneous abortions (SAs)...
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