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Article

Association of MTHFR genetic variants C677T and A1298C on predisposition to spontaneous abortion in Slavonic population.

Clinica chimica acta; international journal of clinical chemistry - 2 Feb 2015

Hubacek Jaroslav A, Rynekrova Jitka, Kasparova Dita, Adamkova Vera, Holmes Michael V, Fait Tomas

Abstract excerpt

AIM: Up to 20% of pregnancies end in the first trimester by spontaneous abortion but the cause of a large proportion remains unexplained. The aim of this study was to investigate the role of two common variants (rs1801133, C677T and rs1801131, A1298C) within the MTHFR gene in the genetic determination of spontaneous abortions. METHODS: DNA from 464 tissue samples of spontaneous abortions and population sample of...

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Source

Identifiers

PMID: 25447701
DOI: 10.1016/j.cca.2014.11.018

Genes

MTHFR

Variants

Provenance

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Association of MTHFR genetic variants C677T and A1298C on predisposition to spontaneous abortion in Slavonic population.PMID 25447701Read ↗

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