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Article

The effects of lifestyle factors on primary biliary cholangitis ascertained by two-sample Mendelian randomization.

The American journal of the medical sciences - 1 Jan 2026

Shen Gang, Sun Hengchang, Guan Xiaoling, Chen Yaqiong, Wang Lin, Li Xinhua, Gong Jiao, Hu Bo

Abstract excerpt

BACKGROUND: Primary biliary cholangitis (PBC) is a chronic liver disease leading to irreversible cirrhosis and liver failure. This study aims to evaluate the relationships between genetically predicted nine lifestyle factors and PBC by Mendelian randomization (MR). METHODS: Genome-wide association study (GWAS) data were utilized to identify genetic variants significantly associated with specific lifestyle...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 41106778
DOI: 10.1016/j.amjms.2025.10.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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