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Article

Colistin- and octenidine-induced selective pressure on Pseudomonas aeruginosa clinical isolates in vitro: Antimicrobial activity and mechanisms of cross-resistance.

Journal of global antimicrobial resistance - 1 Dec 2025

Freire Samanta, Raro Otávio Hallal Ferreira, Nordmann Patrice, Poirel Laurent

Abstract excerpt

OBJECTIVE: Infection prevention using antiseptics is crucial to control the transmission of multidrug-resistant Gram-negative pathogens. METHODS: This in vitro study aimed to evaluate: (1) the susceptibility to octenidine (OCT) of 104 Pseudomonas aeruginosa (including multidrug-resistant) clinical isolates; (2) whether resistant mutants can be obtained by applying selective pressure using increasing...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 41101562
DOI: 10.1016/j.jgar.2025.10.008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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