Article
Octenidine’s Efficacy: A Matter of Interpretation or the Influence of Experimental Setups?
19 Nov 2022
Abstract excerpt
With its broad antimicrobial spectrum and non-specific mode of action via membrane disruption, any resistance to octenidine (OCT) seems unlikely and has not been observed in clinical settings so far. In this study, we aimed to investigate the efficacy of OCT against Escherichia coli and mutants lacking specific lipid head groups which, due to altered membrane properties, might be the root cause for resistance...
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