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Article

Autoimmune Hemolytic Anemia Occurring One Year Before Acute Leukemic Manifestation of Lymphoma with a Chronic Lymphocytic Leukemia Immunophenotype.

Internal medicine (Tokyo, Japan) - 1 Jun 2026

Yoshida Shohei, Watanabe Shinichiro, Ohara Keito, Iguchi Mitsuko, Asagiri Tadashi, Umebara Dai, Kojima Kensuke

Abstract excerpt

We herein report a case of the leukemic phase of chronic lymphocytic leukemia (CLL)-type lymphoma that abruptly developed 12 months after the initial diagnosis of autoimmune hemolytic anemia (AIHA), in which retrospective immunohistochemistry and next-generation sequencing (NGS) revealed that (1) lymphoma with a CLL-type immunophenotype underlay the development of secondary AIHA, (2) complete loss of TP53...

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Share to Anemia, Hemolytic, Autoimmune
Share to TP53 gene

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Immunophenotyping

Share to Leukemia, Lymphocytic, Chronic, B-Cell

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Share to Tumor Suppressor Protein p53

Source

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Identifiers

PMID: 41093550
DOI: 10.2169/internalmedicine.6053-25
PMCID: PMC13294606

Genes

TP53

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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