Article
Autoimmune Lymphoproliferative Syndrome in Children with Nonmalignant Organomegaly, Chronic Immune Cytopenia, and Newly Diagnosed Lymphoma
Turkish journal of haematology : official journal of Turkish Society of Haematology - 1 Jun 2021
Kaya Zühre, Işık Melek, Oruklu Nihan, Kirkiz Serap, Bağrıaçık Emin Ümit, Allende Luis M., Díaz-Madroñero María J., Ruiz-García Raquel, Pınarlı Faruk Güçlü, Göçün Uyar Pınar, Koçak Ülker
Abstract excerpt
This study investigated the frequency of and predictive factors for autoimmune lymphoproliferative syndrome (ALPS) in children with lymphoma, chronic immune cytopenia, and nonmalignant organomegaly. Thirty-four children with suspected ALPS (n=13, lymphoma; n=12, immune cytopenia; n=9, nonmalignant organomegaly) were included. Double-negative T-cells, lymphocyte apoptosis, and genetic findings were analyzed....
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