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EGFR T790M Mutations in Conventional and Langerhans Cell-Rich Variants of CEOT: Unveiling Molecular Differences and Clinical Implications.

Oral diseases - 1 Feb 2026

Zhang Wenyi, Xue Jiang, Sun Lisha, Sun Zhipeng

Abstract excerpt

OBJECTIVES: We aimed to investigate the clinicopathologic and molecular characteristics of conventional and Langerhans cell-rich (LC-rich) variants of Calcifying Epithelial Odontogenic Tumor (CEOT). METHODS: Fifteen patients, eight with conventional and seven with LC-rich variants, were analyzed using clinical data, radiographic features, and histopathologic assessments. A 560-gene cancer panel, utilizing Agilent...

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PMID: 41078249
DOI: 10.1111/odi.70111

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EGFR

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