Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic prediction of blood metabolites and causal relationships with pain associated with temporomandibular disorders: a Mendelian randomization study.

Journal of oral & facial pain and headache - 1 Jun 2025

Zhang Xue'e, Le Ketong, Xi Weihong

Abstract excerpt

BACKGROUND: This study aims to elucidate the causal relationships between 1400 blood metabolites and pain related to temporomandibular disorders (TMD) using Mendelian Randomization (MR) analysis. METHODS: Utilizing data from genome-wide association studies (GWAS), our analysis was conducted with R software using the "TwoSampleMR" package. The primary method applied was Inverse Variance Weighted (IVW) analysis,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carnitine
Share to Genome-Wide Association Study

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mendelian Randomization Analysis

Share to Polymorphism, Single Nucleotide

Share to Temporomandibular Joint Disorders

Source

Open in PubMed Open full text

Identifiers

PMID: 41070543
DOI: 10.22514/jofph.2025.034
PMCID: PMC12520425

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic prediction of blood metabolites and causal relationships with pain associated with temporomandibular disorders: a Mendelian randomization study.PMID 41070543Read ↗

Causal relationship between plasma metabolites and chronic original pain: a Mendelian randomization studySemantic proximity Read ↗

Genetic Association between lipid and the risk of HeadacheSemantic proximity Read ↗

Causal relationships between immunophenotypes, plasma metabolites, and temporomandibular disorders based on Mendelian randomization.Semantic proximity Read ↗

Circulating Metabolites and Dental Traits: A Mendelian Randomization Study.Semantic proximity Read ↗

Exploring the causal effects of sleep characteristics on TMD-related pain: a two-sample Mendelian randomization study.Semantic proximity Read ↗

Genetic insights into the causal role of metabolic, immune, and microbial factors in migraineSemantic proximity Read ↗

Causality of genetically determined metabolites and metabolic pathways on osteoarthritis: a two-sample mendelian randomization study.Semantic proximity Read ↗

Causal Relationship Between Blood Metabolites and Osteoporosis: A Two-Sample Mendelian Randomization and Genetic Correlation AnalysisSemantic proximity Read ↗

The 1400 metabolite-mediated relationship between 91 inflammatory cytokines and migraine: An exploratory two-step Mendelian randomization study.Semantic proximity Read ↗

Evaluating the genetic correlation and causal relationship between osteoarthritis and human blood metabolitesSemantic proximity Read ↗

Genetically determined metabolites in allergic conjunctivitis: A Mendelian randomization studySemantic proximity Read ↗

Exploring the bidirectional relationship between pain and mental disorders: a comprehensive Mendelian randomization study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.