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Genetically determined metabolites in allergic conjunctivitis: A Mendelian randomization study

31 Mar 2024

Abstract excerpt

Background: Allergic conjunctivitis (AC) afflicts a significant portion of the global populace. Yet, its metabolic foundations remain largely unexplored. Methods: We applied Mendelian Randomization (MR) and Linkage Disequilibrium Score Regression (LDSC) to scrutinize a cohort comprising 20 958 AC cases and 356 319 controls. Data were amalgamated from the metabolomics GWAS server and the FinnGen project, under...

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PMID: 38590722
DOI: 10.1016/j.waojou.2024.100894

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