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Article

Enterococcus faecium sagA mutants have cell envelope defects influencing antibiotic resistance and bacteriophage susceptibility.

Journal of bacteriology - 20 Nov 2025

Arya Garima, Chodisetti Pavan Kumar, Espinosa Juliel, Russo Brian C, Hang Howard C, Duerkop Breck A

Abstract excerpt

Enterococcus faecium is a gram-positive bacterium that is resident to the intestines of animals including humans. E. faecium is also an opportunistic pathogen that causes multidrug-resistant (MDR) infections. Bacteriophages (phages) have been proposed as therapeutics for the treatment of MDR infections; however, an obstacle for phage therapy is the emergence of phage resistance. Despite this, the development of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41065453
DOI: 10.1128/jb.00302-25
PMCID: PMC12632251

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