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Caenorhabditis elegans AWC neuron-mediated chemosensation negatively modulates dormancy during Salmonella fepB mutant infection.

Microbiology spectrum - 4 Nov 2025

Mallick Swarupa, Pradhan Jasmin, Daimai Chamjailiu, Negi Vidya Devi

Abstract excerpt

In our earlier work, we demonstrated that continuous 8-day exposure of Caenorhabditis elegans to a Salmonella enterica serovar Typhimurium fepB mutant strain negatively regulates dauer larva development in the second generation of the population. Our current study aims to understand how specific chemosensory neurons in C. elegans recognize the ∆fepB Salmonella Typhimurium strain and undergo plasticity in response...

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Identifiers

PMID: 41060009
DOI: 10.1128/spectrum.00420-25
PMCID: PMC12584732

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