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Loss of cilia in chemosensory neurons inhibits pathogen avoidance in Caenorhabditis elegans.

Microbes and infection - 1 Jan 2024

Lei Ming, Tan Yanheng, Ke Jingyi, Wang Mengqi, He Zeyang, Ou Guangshuo, Tu Haijun, Tan Weihong

Abstract excerpt

Pathogen avoidance is a crucial and evolutionarily conserved behavior that enhances survival by preventing infection in diverse species, including Caenorhabditis elegans (C. elegans). This behavior relies on multiple chemosensory neurons equipped with cilia that are exposed to the external environment. However, the specific role of neuronal cilia in pathogen avoidance has not been completely elucidated. Herein,...

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PMID: 38843949
DOI: 10.1016/j.micinf.2024.105370

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