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Generating human primordial germ cell-like cells from pluripotent stem cells: a scoping review of in vitro methods

1 Jan 2025

Abstract excerpt

STUDY QUESTION: compare to each other? SUMMARY ANSWER: All analyzed protocols were successful in generating hPGCLCs, and a few were able to induce further germ cell maturation. WHAT IS KNOWN ALREADY: -derived hPGCLCs in research and the advancement toward generating mature germ cells. STUDY DESIGN SIZE DURATION: For this scoping review, a systematic search for protocols was conducted in the databases Scopus and...

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PMID: 41018120
DOI: 10.1093/hropen/hoaf056

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