Article
The lamin protein family.
Genome biology - 1 Jan 2011
Dittmer Travis A, Misteli Tom
Abstract excerpt
The lamins are the major architectural proteins of the animal cell nucleus. Lamins line the inside of the nuclear membrane, where they provide a platform for the binding of proteins and chromatin and confer mechanical stability. They have been implicated in a wide range of nuclear functions, including higher-order genome organization, chromatin regulation, transcription, DNA replication and DNA repair. The lamins...
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