Article
Enrich: software for analysis of protein function by enrichment and depletion of variants.
Bioinformatics (Oxford, England) - 15 Dec 2011
Fowler Douglas M, Araya Carlos L, Gerard Wayne, Fields Stanley
Abstract excerpt
SUMMARY: Measuring the consequences of mutation in proteins is critical to understanding their function. These measurements are essential in such applications as protein engineering, drug development, protein design and genome sequence analysis. Recently, high-throughput sequencing has been coupled to assays of protein activity, enabling the analysis of large numbers of mutations in parallel. We present Enrich, a...
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